December 5, 2023

Danish drugmaker Novo Nordisk stated Tuesday that outcomes from a latest drug trial demonstrated that its extremely sought weight reduction drug Wegovy additionally reduces the danger of coronary heart illness. 

Novo stated the outcomes from the late-stage drug trial confirmed sufferers taking the weekly injection of semaglutide, the lively ingredient in Wegovy, had a 20% decrease danger of coronary heart assault, stroke or demise from coronary heart illness in comparison with these taking a placebo.

The corporate’s inventory jumped Tuesday after the outcomes beat analyst expectations. Traders and analysts beforehand projected that the drug would cut back the danger of coronary heart illness by 15%-17%, based on Reuters. 

Packets of Wegovy transfer alongside a conveyor on the Novo Nordisk A/S manufacturing plant in Hillerod, Denmark, June 12, 2023.  (Carsten Snejbjerg/Bloomberg through Getty Photographs / Getty Photographs)

The purpose of the corporate’s giant drug trial, which concerned over 17,600 adults, was to evaluate whether or not Wegovy has a medical profit and may cut back the danger of main cardiovascular occasions like strokes or coronary heart assaults along with serving to individuals shed pounds. 

WEGOVY, OZEMPIC: THE BARRIERS TO ACCESSING THESE WEIGHT LOSS DRUGS

The Meals and Drug Administration (FDA) first permitted Wegovy in 2021 for persistent weight administration in adults who’re overweight or chubby and have no less than one weight-related situation, similar to hypertension, Sort 2 diabetes or excessive ldl cholesterol. 

In keeping with the World Well being Group (WHO), cardiovascular illnesses are the main reason for demise globally with an estimated 17.9 million individuals dying from such illnesses in 2019. Of these deaths, 85% have been resulting from coronary heart assault and stroke, based on WHO. 

Wegovy

Varied packages of the burden loss drug “Wegovy” from the pharmaceutical firm Novo Nordisk on a gross sales counter in a Danish pharmacy.  (Steffen Trumpf/image alliance through Getty Photographs / Getty Photographs)

“Folks dwelling with weight problems have an elevated danger of heart problems however, up to now, there are not any permitted weight administration medicines confirmed to ship efficient weight administration whereas additionally decreasing the danger of coronary heart assault, stroke or cardiovascular demise,” Martin Holst Lange, government vp for growth at Novo Nordisk, stated in a press release. 

DIABETES-RELATED WEIGHT-LOSS DRUGS FACING SUPPLY ISSUES AMID VIRAL TREND

The corporate expects to file for regulatory approvals of a label indication growth for Wegovy within the U.S. and the European Union this 12 months. Particulars from the drug trial will likely be offered at a scientific convention later this 12 months, based on Novo. 

Novo additionally manufactures Ozempic, which is similar remedy as Wegovy however has totally different dosages and FDA-approved supposed makes use of.

ozempic

The anti-diabetic remedy Ozempic made by Danish pharmaceutical firm Novo Nordisk. (Joel Saget/AFP through Getty Photographs / Getty Photographs)

Ozempic was permitted by federal well being officers in 2017 and marketed for medical use within the therapy of Sort 2 diabetes “with weight reduction as a secondary impact of the drug’s results and mechanism of motion.”

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Weogvy and Ozempic surged in recognition after high-profile figures touted their weight reduction results. The demand surged a lot that it prompted a short lived scarcity.